The complete nucleotide sequence of the trpC gene from Penicillium chrysogenum.

gisol that shows a high hosology with the products of Aspergilius nidulans r!jC gene i3) and leurospora crassa try-l gene 4) (71.5% and 630. respectively), strongly suggesting that: fi! the protein is a trifunctional polypepride containing the glutraine aslidc transferase GAT), indoleglycerolphophate synchase IGPS) and phosphoribosylanthranilate isoserase PRAII activities of the tryptophan biosynthetic pathway in the crder NH2-GAT-iGPS-PRA1-COCH: tii) the gene does not contain introns as expected fros its direct expression in E. ccli 1)l.